Invasive gastric carcinoma with metastasis to the small intestine and colon simulating stenosing Crohn disease

case report

Authors

  • Igor Gonçalves Sant’Ana Universidade Federal do Espírito Santo
  • Thaisa de Moraes Ribeiro Espírito Santo Hospital Universitário Cassiano Antonio Moraes
  • Marilia Majeski Colombo Hospital Universitário Cassiano Antonio Moraes

DOI:

https://doi.org/10.47456/rbps.v26i1.51183

Keywords:

Crohn Disease, Stomach Neoplasms, Neoplasm Metastasis

Abstract

Introduction: Signet ring cell gastric cancer is an aggressive neoplasm, with rare metastases to the intestines. However, when it occurs, it can cause intestinal subocclusion syndrome, although it can generate nonspecific symptoms, which makes diagnosis difficult. Objectives: Report a rare case of gastric cancer with metastases to the small intestine and colon, simulating Crohn's disease, thus helping physicians to broaden their vision for differential diagnoses when faced with similar cases. Methods: Data collection from the patient's medical records. Case presentation: Woman, 71 years old, with recurrent intestinal subocclusion and unintentional weight loss, with severe impairment of nutritional status. Colonoscopy showed an insurmountable stenosing lesion in the right colon, in addition to abdominal tomography showing stenosis of small bowel loops with upstream dilatation and colonic stenosis associated with signs suggestive of a local inflammatory process. Upper digestive endoscopy showed ulceroinfiltrative lesion in the gastric antrum with histopathology indicative of invasive signet ring cell gastric carcinoma. The patient was not clinically fit for curative chemotherapy or surgical treatment, and an attempt at strictureplasty and/or enterectomy was chosen to improve the quality of life. However, exploratory laparotomy revealed intestinal metastases secondary to gastric neoplasia, and the diagnosis of Crohn's disease was ruled out. Conclusion: Despite being a rare presentation, intestinal metastasis from gastric cancer can occur and simulate other conditions, such as Crohn's disease, becoming a diagnostic challenge, especially when it affects loops of the small intestine.

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References

Mehershahi S, Mantri N, Sun H, Shaikh D, Patel H. Metastasis from gastric signet ring cell adenocarcinoma presenting as a rectosigmoid stricture: a rare case. Cureus. 2020 Jun 10;12(6):e8552. https://doi.org/10.7759/cureus.8552. PMID: 32670689; PMCID: PMC7357336

Fagundes MA, Peres SV, Assumpção PP, Curado MP. Physical activity and gastric cancer risk: a case-control study in the Amazon region of Brazil. Eur J Cancer Prev. 2021 Nov 1;30(6):437–41. https://doi.org/10.1097/CEJ.0000000000000654. PMID: 33369944

Barchi LC, Ramos MFKP, Dias AR, Forones NM, Carvalho MP, Castro OAP, et al. Brazilian gastric cancer association guidelines (part 1): update on treatment. Arq Bras Cir Dig. 2021 May 14;34(1):e1563. https://doi.org/10.1590/0102-672020210001e1563. PMID: 34008707; PMCID: PMC8121052

Cesaretti M, Malerba M, Basso V, Boccardo C, Santoni R, D’Alessandro G, et al. Cutaneous metastasis from primary gastric cancer: a case report and review of the literature. Cutis. 2014 Apr;93(4):E9–13. PMID: 24818191

Tang L, Li H, Lv J, Fang C, Zhang H, Meng J. Rectal metastasis of gastric cancer: a case report. J Int Med Res. 2023 Oct;51(10):3000605231198407. https://doi.org/10.1177/03000605231198407. PMID: 37815339; PMCID: PMC10566277

Kohno S, Ikegami M, Yamamoto SR, Aoki H, Ogawa M, Yano F, Eto K. A rare case of colorectal metastasis found 8 years and 10 months after gastrectomy for advanced gastric cancer: a case report and literature review. Oncol Lett. 2023 Apr 5;25(5):203. https://doi.org/10.3892/ol.2023.13789. PMID: 37123025; PMCID: PMC10131265

Tariq T, Turk A, Reaume M, Muddasani A, Parmar M. Blocked by a ring: a case of gastric linitis plastica presenting as large bowel obstruction secondary to rectal stenosis. ACG Case Rep J. 2019 Mar 6;6(2):e00007. https://doi.org/10.14309/crj.0000000000000007. PMID: 31616715; PMCID: PMC6657991

Fan Q, Su M. Isolated small bowel metastasis from gastric cancer detected by 18F-FDG PET/CT. Clin Nucl Med. 2019 Oct;44(10):840–1. https://doi.org/10.1097/RLU.0000000000002702. PMID: 31283609

Bilimoria KY, Bentrem DJ, Wayne JD, Ko CY, Bennett CL, Talamonti MS. Small bowel cancer in the United States: changes in epidemiology, treatment, and survival over the last 20 years. Ann Surg. 2009 Jan;249(1):63–71. https://doi.org/10.1097/SLA.0b013e31818e4641. PMID: 19106677

Vlachou E, Koffas A, Toumpanakis C, Keuchel M. Updates in the diagnosis and management of small-bowel tumors. Best Pract Res Clin Gastroenterol. 2023 Jun–Aug;64–65:101860. https://doi.org/10.1016/j.bpg.2023.101860. Epub 2023 Aug 12. PMID: 37652650

Mishima M, Sakurai T, Miyamoto S. Intramucosal metastasis of gastric cancer to the duodenum. Clin Gastroenterol Hepatol. 2019 Dec;17(13):A27. https://doi.org/10.1016/j.cgh.2018.08.006. Epub 2018 Aug 9. PMID: 30099103

Shima T, Arita A, Sugimoto S, Takayama S, Kawaguchi N, Imai Y, et al. Metástase colônica simultânea de câncer gástrico avançado: relato de caso. Surg Case Rep. 2023;9:39. https://doi.org/10.1186/s40792-023-01622-x

Costa-Silva L, Brandão AC. MR enterography for the assessment of small bowel diseases. Magn Reson Imaging Clin N Am. 2013 May;21(2):365–83. https://doi.org/10.1016/j.mric.2013.01.005. Epub 2013 Feb 19. PMID: 23642558

Pellino G, Nicolai E, Catalano OA, Campione S, D’Armiento FP, Salvatore M, Cuocolo A, Selvaggi F. PET/MR versus PET/CT imaging: impact on the clinical management of small-bowel Crohn’s disease. J Crohns Colitis. 2016 Mar;10(3):277–85. https://doi.org/10.1093/ecco-jcc/jjv207. Epub 2015 Nov 15. PMID: 26574490; PMCID: PMC4957472

Published

2024-12-31

Issue

Section

Dossier: Medical Residency Commission (COREME-HUCAM)

How to Cite

1.
Invasive gastric carcinoma with metastasis to the small intestine and colon simulating stenosing Crohn disease: case report. RBPS [Internet]. 2024 Dec. 31 [cited 2026 May 17];26(1):e51183. Available from: https://ojs3.ufes.br/rbps/article/view/51183

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